When it comes to anabolic steroids, Superdrol and Clostebol are two names that resonate with athletes and bodybuilders alike, each promising remarkable muscle gains and enhanced performance. But which one truly reigns supreme in the world of anabolic powerhouses? Superdrol, renowned for its impressive strength-boosting capabilities, has earned a reputation for delivering rapid results and a lean physique. In contrast, Clostebol, with its unique properties, tends to be favoured for its milder side effects and versatility in cutting cycles.

As we dive deeper into the mechanics, benefits, and potential downsides of Superdrol and Clostebol, you’ll discover crucial insights that will help you make an informed choice.

Strap in for a comprehensive showdown that pits these two anabolic titans against each other—because in the quest for peak performance, knowledge is just as powerful as the substances themselves.

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Superdrol vs. Clostebol: A Comparison of Two Anabolic Steroids

Overview of Superdrol

Superdrol, known chemically as methasterone, has earned its place among the elite anabolic steroids due to its potent muscle-building capabilities and significant strength enhancement. Originally developed in the 1950s for therapeutic purposes, Superdrol eventually entered the bodybuilding world, where it gained popularity for delivering rapid and dramatic results.

Despite its brief stint on the supplement market in the early 2000s, Superdrol quickly gained a reputation for enabling users to achieve rapid increases in lean muscle mass and strength. These effects are particularly appealing to competitive athletes and bodybuilders looking to transform their physique in a short amount of time.

One of Superdrol's key advantages is its oral administration, eliminating the need for injections. As a DHT-derived steroid, Superdrol does not aromatize into estrogen, which minimizes the risk of estrogenic side effects like gynecomastia and water retention. However, this convenience comes at a cost—Superdrol is highly hepatotoxic, meaning liver support and cautious dosing are essential.

The anabolic activity of Superdrol is attributed to its ability to enhance protein synthesis and nitrogen retention, two processes fundamental to muscle repair and growth. Users often report dramatic improvements in strength, size, and muscle hardness within 2–4 weeks of starting a cycle.

"Superdrol's rapid gains are tied to its anabolic rating of 400, far exceeding testosterone’s baseline of 100, making it one of the most potent oral steroids available" (William Llewellyn, Anabolics).

Risks and Considerations

• Hepatotoxic: Superdrol is methylated, making liver toxicity a serious concern.

• Androgenic effects: Acne, hair loss, and mood changes may occur.

• Testosterone suppression: Natural production is significantly suppressed, requiring proper post-cycle therapy (PCT).

Overview of Clostebol

Clostebol, or 4-chlorotestosterone, is a milder anabolic steroid with a favorable safety profile, originally developed for medical use to treat conditions such as muscle wasting and osteoporosis. Its balanced anabolic-to-androgenic ratio makes it an attractive option for athletes and bodybuilders who are sensitive to side effects or seeking moderate, steady results.

Clostebol is available in both injectable (Clostebol acetate) and oral (Megagrisevit) forms, offering flexibility in administration. Injectable forms are preferred for their longer half-life, while oral versions are ideal for convenience and compliance.

Compared to Superdrol, Clostebol offers a more gradual approach to muscle building. While it may not produce explosive gains, it provides consistent improvements in lean muscle mass, recovery, and athletic performance with fewer risks.

"Clostebol is structurally similar to testosterone but with a chlorine atom that prevents aromatization, resulting in anabolic effects without estrogenic complications" (Kicman, British Journal of Pharmacology).

Benefits and Applications

• No aromatization: No risk of estrogen-related side effects like water retention or gynecomastia.

• Low androgenic activity: Reduced likelihood of acne, aggression, or hair loss.

• Ideal for cutting cycles: Helps preserve lean muscle while reducing fat.

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Mechanism of Action: How Each Steroid Works

Superdrol

Superdrol (methasterone) functions as a DHT-derived oral anabolic steroid that binds strongly to androgen receptors in skeletal muscle tissue. This interaction stimulates protein synthesis, which is crucial for building and repairing muscle fibers. It also enhances nitrogen retention, helping maintain a positive nitrogen balance, which supports an anabolic environment within the body.

In addition to muscle-building, Superdrol promotes erythropoiesis (red blood cell production), which improves oxygen transport during training sessions. This mechanism delays fatigue and contributes to enhanced workout endurance.

However, due to its 17α-alkylated structure, Superdrol is highly hepatotoxic, placing considerable strain on the liver even at moderate doses.

“Superdrol’s structure allows it to resist breakdown by the liver, making it effective orally—but this also significantly increases its toxicity” (William Llewellyn, Anabolics).

Clostebol

Clostebol (4-chlorotestosterone), a chlorinated derivative of testosterone, also binds to androgen receptors, albeit with less potency than Superdrol. This leads to gradual increases in protein synthesis and nitrogen retention, promoting steady gains in lean muscle tissue.

Unlike testosterone, Clostebol does not aromatize into estrogen, meaning there is minimal risk of estrogen-related side effects such as gynecomastia or water retention. Its low androgenic index also reduces the likelihood of acne, aggression, and hair loss.

“The 4-chloro modification in Clostebol blocks aromatization, reducing estrogenic and androgenic side effects while preserving anabolic activity” (Kicman, British Journal of Pharmacology).

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Benefits of Superdrol

1. Rapid Muscle Mass Gains

Superdrol is renowned for delivering fast, dramatic increases in muscle size, with many users seeing visible changes within 2–4 weeks. These results are driven by its ability to accelerate protein synthesis and enhance cellular hypertrophy.

2. Increased Strength and Training Capacity

Users often report impressive improvements in strength, enabling heavier lifts and more intense workouts. Superdrol also boosts endurance by improving oxygen delivery through enhanced red blood cell production.

3. No Estrogenic Activity

As a non-aromatizing DHT derivative, Superdrol avoids common estrogen-related side effects, such as:

• Water retention

• Bloating

• Gynecomastia

4. Muscle Hardness and Definition

Because it avoids water retention, Superdrol contributes to a dry, vascular, and chiseled appearance, making it appealing during cutting phases as well as bulking.

“Unlike testosterone derivatives that convert to estrogen, Superdrol provides dry gains that promote definition and vascularity” (Miller, Steroid Profiles Handbook).

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Benefits of Clostebol

1. Lean Muscle Growth with Low Bloat

Clostebol promotes slow but steady gains in lean muscle mass without significant water retention, making it especially suitable for cutting cycles or for athletes who prioritize physique aesthetics.

2. Minimal Androgenic and Estrogenic Side Effects

Clostebol is well-tolerated by most users. Its non-aromatizing nature significantly reduces risks of gynecomastia or estrogen-induced fat gain. Its lower androgenic index also makes it a suitable choice for those prone to:

• Acne

• Scalp hair loss

• Mood swings

“Clostebol’s reputation for safety stems from its weak androgenic activity, which allows long-term use with minimal side effects” (Llewellyn, Anabolics).

3. Versatile Administration

Available in both injectable (Clostebol acetate) and oral (Megagrisevit) forms, Clostebol provides flexibility. While injectable forms offer stable blood levels and longer half-lives, the oral version is convenient for first-time users or those averse to needles.

4. Enhanced Recovery

Users note improved recovery times between workouts, making Clostebol helpful for athletes in sports requiring frequent or high-volume training.

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Potential Side Effects of Superdrol

Despite its powerful anabolic benefits, Superdrol comes with significant risks, particularly related to liver toxicity and cardiovascular health.

1. Hepatotoxicity

Superdrol is a 17α-alkylated compound, which allows it to survive first-pass metabolism in the liver—but this also significantly elevates liver strain. Prolonged or high-dose use can lead to:

• Elevated liver enzymes (AST/ALT)

• Hepatocellular damage

• Jaundice or other liver-related symptoms

“17-alpha alkylated steroids like Superdrol pose a clear risk to liver health and should be used with caution” (Hartgens & Kuipers, Sports Medicine).

Recommendations:

• Limit cycles to 4–6 weeks

• Use liver support supplements (e.g., milk thistle, NAC, TUDCA)

• Avoid alcohol and hepatotoxic medications during use

2. Cholesterol Imbalance

Superdrol can drastically lower HDL (good cholesterol) and raise LDL (bad cholesterol), contributing to:

• Arterial plaque buildup

• Increased risk of heart attack or stroke

Users should monitor lipid panels regularly and adopt a heart-healthy diet, including:

• Omega-3 fatty acids (e.g., krill oil)

• Soluble fiber

• Cardio-focused exercise regimens

“Anabolic steroids negatively impact the lipid profile, increasing the risk of atherosclerosis” (Glazer, The American Journal of Medicine).

3. Androgenic Effects

Though Superdrol does not aromatize, it retains strong androgenic properties, which may lead to:

• Acne

• Scalp hair loss (especially in those predisposed to male pattern baldness)

• Increased body or facial hair

“Androgenic side effects vary with individual sensitivity to DHT derivatives like Superdrol” (Llewellyn, Anabolics).

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Potential Side Effects of Clostebol

Clostebol is generally considered a milder steroid, but it still carries some risks—especially if used improperly or at high dosages.

1. Testosterone Suppression

Clostebol can suppress natural testosterone production, especially with prolonged use. Post-cycle symptoms may include:

• Fatigue

• Decreased libido

• Mood swings

• Loss of muscle mass

A proper post-cycle therapy (PCT) is essential to recover hormonal balance.

“Even mild anabolic steroids can cause substantial suppression of endogenous testosterone over time” (Kicman, British Journal of Pharmacology).

2. Hepatotoxicity (Primarily Oral Form)

Although Clostebol is less liver-toxic than Superdrol, its oral form (Megagrisevit) still poses mild hepatotoxicity risk. Users should:

• Limit cycle length (4–6 weeks max for orals)

• Monitor liver enzymes

• Use liver support supplements proactively

Injectable Clostebol (acetate) largely avoids this issue due to bypassing first-pass metabolism.

3. Androgenic Side Effects

At higher doses, Clostebol may still produce androgenic effects such as:

• Oily skin and acne

• Increased facial or body hair

• Hair thinning or loss (in genetically susceptible individuals)

“Although Clostebol has weaker androgenic activity, androgen-related side effects remain possible, particularly at supratherapeutic doses” (Basaria, The Journal of Clinical Endocrinology & Metabolism).

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Post-Cycle Therapy (PCT) Protocol After Superdrol or Clostebol

Why PCT Is Essential

Both Superdrol and Clostebol suppress natural testosterone production. Without proper PCT, users risk:

• Prolonged low testosterone

• Muscle loss

• Mood disturbances

• Low libido

• Increased estrogen dominance

A well-structured PCT helps restore natural hormone balance, preserve muscle gains, and reduce side effects after the cycle ends.

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PCT Timing

• Superdrol: Begin 3 days after last dose due to its short half-life (8–12 hours)

• Clostebol: Begin 4–5 days after last dose (oral) or 7–10 days after last injection (acetate)

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Recommended PCT Duration

• Length: 4–6 weeks

• Goal: Restore HPTA (hypothalamic-pituitary-testicular axis) and natural testosterone production

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Core PCT Protocol

Supplement / Drug	Dosage	Duration	Purpose
Tamoxifen (Nolvadex)	40 mg/day (Week 1–2) → 20 mg/day (Week 3–4)	4 weeks	Boost LH/FSH, restart testosterone
Clomiphene (Clomid) (optional addition to Nolvadex)	50 mg/day	4 weeks	Synergistic restart of testosterone
Swolverine ZMT	6 capsules nightly	4–6 weeks	Natural test support, mood, libido, sleep
Swolverine DHEA	100 mg/day	4–6 weeks	Adrenal androgen support and energy
Swolverine Krill Oil	2–3 softgels/day	4–6 weeks	Cardiovascular and cholesterol recovery
TUDCA or NAC (for Superdrol)	TUDCA 500 mg/day or NAC 1200–1800 mg/day	4–6 weeks	Liver detoxification support
Vitamin D3 + Zinc	D3: 3000–5000 IU/day, Zinc: 30–50 mg/day	4 weeks	Testosterone and immune health

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Additional Recovery Tips

• Diet: Prioritize protein, omega-3s, cruciferous vegetables, and micronutrients

• Training: Reduce volume/intensity by 20–30% during PCT to aid recovery

• Sleep: Aim for 7–9 hours per night to normalize hormones

• Bloodwork: Test testosterone, estradiol, LH, FSH, liver enzymes, and lipids before, during, and after PCT

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Example PCT Stack (Swolverine-Integrated)

Weeks 1–4:

• Tamoxifen: 40/40/20/20 mg

• ZMT: 6 caps nightly

• DHEA: 100 mg/day (morning)

• Krill Oil: 2–3 softgels/day

• TUDCA or NAC: (Superdrol only)

Weeks 5–6 (optional taper):

• ZMT: continue

• DHEA: taper to 50 mg/day

• Krill Oil: continue

“Post-cycle therapy is critical to restore endocrine function after anabolic steroid cycles and prevent long-term hypogonadism” (Basaria, The New England Journal of Medicine).

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Frequently Asked Questions (FAQ)

1. Is Superdrol still legal to buy?

No. In the United States, Superdrol (methasterone) is classified as a Schedule III controlled substance. It was banned in 2012 due to its potent anabolic effects and serious health risks. Possessing or selling Superdrol without a prescription is illegal and punishable under federal law.

“Superdrol was reclassified as an anabolic steroid under the Anabolic Steroid Control Act due to its risks to liver health and hormonal balance” (FDA, Drug Safety Communication).

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2. Is Clostebol a safe alternative to Superdrol?

Clostebol is considered a milder anabolic steroid compared to Superdrol. While it carries fewer risks of liver toxicity, cholesterol disruption, and androgenic side effects, it can still suppress natural testosterone production and may cause issues at high doses or with long-term use. It is a safer option, but not without risks.

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3. Do I need PCT after a Clostebol cycle?

Yes. Even though Clostebol is mild, it still suppresses endogenous testosterone. A post-cycle therapy (PCT) is strongly recommended to:

• Restore natural testosterone production

• Maintain muscle mass

• Prevent mood swings, fatigue, and low libido

A Nolvadex-based PCT with support from natural test boosters like Swolverine ZMT and DHEA is ideal.

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4. What makes Superdrol so effective for muscle growth?

Superdrol has an anabolic rating of ~400 (4x that of testosterone), making it extremely effective for rapid gains in muscle size and strength. It:

• Increases protein synthesis

• Enhances nitrogen retention

• Improves red blood cell production

However, these benefits come with a high cost to liver health and cholesterol levels, making it suitable only for experienced users willing to manage its side effects.

“Methasterone’s structure allows rapid anabolic responses, but also carries serious liver toxicity risks” (Llewellyn, Anabolics).

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5. Can women use Clostebol safely?

Clostebol has been used in clinical settings for women, but its androgenic properties still pose risks, such as:

• Voice deepening

• Menstrual irregularities

• Facial hair growth

For performance purposes, it is generally not recommended for women unless prescribed and monitored by a physician.

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6. Which steroid is better for cutting: Superdrol or Clostebol?

Clostebol is the better choice for cutting. It helps maintain lean muscle mass during calorie restriction without causing water retention or bloating. Superdrol, while not aromatizing, can still lead to bloating due to toxicity-related water retention and may be too harsh for a caloric deficit phase.

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7. How long should a Superdrol or Clostebol cycle last?

• Superdrol: 3–4 weeks max (due to liver toxicity)

• Clostebol: 6–8 weeks (oral), or 8–10 weeks (injectable acetate)

Always follow up with PCT and consider liver health, testosterone suppression, and your training goals when planning cycle length.

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8. Can I stack Superdrol with Clostebol?

While technically possible, stacking these two orally active steroids is not recommended due to cumulative strain on the liver and increased testosterone suppression. A better option would be stacking Clostebol with a low-dose injectable base (e.g., testosterone enanthate) and using Superdrol as a standalone short-cycle kickstart—only if you're experienced.

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Legal Status and Availability of Superdrol and Clostebol

Superdrol

Superdrol (methasterone) was once marketed as a legal prohormone supplement in the early 2000s but was later banned by the FDA due to its potent anabolic effects and high hepatotoxicity. It was reclassified as an anabolic steroid and added to the Controlled Substances list (Schedule III) under the Anabolic Steroid Control Act of 2004.

Today, Superdrol is illegal to possess or distribute in the U.S. without a prescription, and there are no FDA-approved medical uses. Most users now obtain it through black market sources, which increases the risks of:

• Counterfeit or contaminated products

• Unlabeled dosages

• Legal consequences

“The FDA issued warnings and recalls for products containing methasterone due to liver toxicity risks and reclassified it as a Schedule III anabolic steroid” (FDA, Drug Safety Communication).

Clostebol

Clostebol (4-chlorotestosterone) has approved medical uses in some countries, including Italy and parts of Eastern Europe, where it is prescribed for:

• Muscle wasting conditions

• Osteoporosis

• Post-surgical recovery

However, in the United States, Clostebol is also classified as a Schedule III controlled substance, meaning it is illegal for non-medical or athletic use. Furthermore, Clostebol is listed as a prohibited substance by WADA (World Anti-Doping Agency), and athletes testing positive may face suspensions or bans.

“Clostebol is prohibited at all times, both in and out of competition, according to the WADA Prohibited List” (WADA, Prohibited List).

Like Superdrol, Clostebol is often sourced through underground markets when used for performance enhancement, carrying similar legal and health risks.

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Conclusion: Choosing the Right Anabolic Steroid for Your Goals

When deciding between Superdrol and Clostebol, users must weigh the benefits against the potential health risks and legal implications.

Choose Superdrol if:

• Your goal is maximum mass and strength gains in a short time

• You have previous experience with oral anabolic steroids

• You’re prepared to manage serious side effects, including liver toxicity and cholesterol suppression

But be aware: Superdrol is extremely potent, highly suppressive, and legally restricted in many countries.

Choose Clostebol if:

• You prefer gradual, steady lean muscle gains

• You want a safer, more versatile compound with lower androgenic effects

• You're aiming for aesthetic improvements during a cutting cycle with lower water retention

Clostebol is more suitable for longer-term use, especially for those concerned with side effect management, but legal access is still heavily restricted in the U.S.

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Always consult with a qualified healthcare professional before considering anabolic steroid use. These compounds carry significant health risks and legal consequences. For safer alternatives, consider evidence-backed supplements such as Swolverine DHEA, ZMT for hormone support, and Krill Oil to promote performance, recovery, and hormone balance.